The study provides support for the biosynthetic route of nargenicin and absolute configuration.
2.
Until 1951 it was not possible to obtain the absolute configuration of chiral compounds.
3.
The absolute configuration was determined the comparison of calculated and experimental vibrational circular dichroism.
4.
The measurement of absolute configuration is also facilitated by the presence of atoms heavier than oxygen.
5.
The crystal structure of butaclamol hydrobromide and the absolute configuration and crystal structure of dexclainol hydrobromide.
6.
It is also interesting that the olefin product s absolute configuration mimics that of Balaram s disulfide peptide.
7.
The concept of Fischer, who had used glyceraldehyde as the prototype and assigned randomly its absolute configuration.
8.
In 1990, Barry Trost presented an enantioselective synthesis of rocaglamide in 18 steps and confirmed its absolute configuration.
9.
Absolute configurations for a chiral molecule ( in pure form ) are most often obtained by X-ray crystallography.
10.
Shorter wavelengths make the observable differences in measured intensities smaller, thereby making the distinction of absolute configuration more difficult.
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